
Thermo Fisher Scientific NPPB Monoclonal Antibody (OTI12B6), TrueMAB
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인간 NPPB 단백질(아미노산 27-102)을 인식하는 Mouse IgG1 단클론 항체. Western blot에 최적화되어 있으며, 심혈관 관련 연구에 적합. 액상 형태로 1 mg/mL 농도, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12B6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 27–102 of human NPPB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene is a member of the natriuretic peptide family and encodes a secreted protein functioning as a cardiac hormone. The protein undergoes two cleavage events—one intracellular and one after secretion into the blood. Its biological actions include:
- Natriuresis
- Diuresis
- Vasorelaxation
- Inhibition of renin and aldosterone secretion
It plays a key role in cardiovascular homeostasis. Elevated levels in the bloodstream are indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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