Thermo Fisher Scientific DHCR24 Polyclonal Antibody
DHCR24 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(paraffin) 실험에 적합하며, 높은 특이성과 재현성을 제공. 액상 형태로 1 mg/mL 농도, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DHCR24 (Accession Q15392), corresponding to amino acid residues R65–M115 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815711 |
Product Specific Information
Antibody detects endogenous levels of total Seladin 1.
Target Information
DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase that catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis.
This protein contains a leader sequence that directs it to the endoplasmic reticulum membrane.
Missense mutations in this gene have been associated with desmosterolosis.
Reduced expression of this gene occurs in the temporal cortex of Alzheimer’s disease patients, while overexpression has been observed in adrenal gland cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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