Thermo Fisher Scientific EYA4 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.04–0.4 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:20–1:50

Product Specifications

Product Specific Information

Immunogen sequence:
QYAQYYSAST YGAYMTSNNT ADGTPSSTST YQLQESLPGL TNQPGEFDTM QSPSTPIKDL DERTCRSSGS KS

Highest antigen sequence identity to the following orthologs:

• Mouse: 93%
• Rat: 93%

Target Information

This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator through its protein phosphatase activity, and it may be important for eye development and the function of the mature organ of Corti.
Mutations in this gene are associated with postlingual, progressive, autosomal dominant hearing loss at the deafness, autosomal dominant non-syndromic sensorineural 10 locus.
The encoded protein is also a putative oncogene that mediates DNA repair, apoptosis, and innate immunity following DNA damage, cellular damage, and viral attack.
Defects in this gene are associated with dilated cardiomyopathy 1J.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

제품 이미지

(이미지 없음)