Thermo Fisher Scientific RAB40B Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human RAB40B(Accession Q12829), corresponding to amino acid residues R234-S278. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RAB40B,uniProtId:Q12829-1,ncbiNodeId:9606,antigenRange:234-278,antigenLength:278,antigenImageFileName:PA5-106719_RAB40B_Q12829-1_Rabbit.svg,antigenImageFileNamePDP:PA5-106719_RAB40B_Q12829-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2854387

Product Specific Information

Antibody detects endogenous levels of total RAB40B.

Target Information

Rab 40B is a 278 amino acid protein that belongs to the small GTPase superfamily and the Rab family. Rab 40B contains a SOCS box domain that mediates interactions with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes. Rab 40B shares similarity with a yeast protein, suggesting a role in regulation of secretory vesicles. The Rab 40B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 17q25.3. It has been suggested that there is a major gene locus on chromosome 17q25.3 for autosomal dominant moyamoya disease (MMD), which is an idiopathic steno-occlusive cerebrovascular disease that represents an important cause of stroke.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.