Thermo Fisher Scientific RAB40B Polyclonal Antibody
RAB40B 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 면역세포화학(ICC/IF)에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RAB40B (Accession Q12829), corresponding to amino acid residues R234–S278 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854387 |
Product Specific Information
Antibody detects endogenous levels of total RAB40B.
Target Information
Rab 40B is a 278 amino acid protein belonging to the small GTPase superfamily and the Rab family. It contains a SOCS box domain that mediates interactions with the Elongin BC complex, an adapter module in various E3 ubiquitin ligase complexes. Rab 40B shares similarity with a yeast protein, suggesting a role in the regulation of secretory vesicles. The Rab 40B gene is conserved across multiple species including chimpanzee, cow, mouse, rat, chicken, and zebrafish, and maps to human chromosome 17q25.3. A major gene locus on chromosome 17q25.3 has been associated with autosomal dominant moyamoya disease (MMD), an idiopathic steno-occlusive cerebrovascular condition linked to stroke.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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