Thermo Fisher Scientific Histone H1.4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Histone H1.4 (HIST1H1E) N-terminal region. Validated for Western blot applications. High purity via affinity chromatography. Supplied as liquid in PBS with 2% sucrose. For research use only.
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Applications
Western Blot (WB)
- Tested dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human HIST1H1E (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609529 |
Product Specific Information
- Peptide sequence: MSETAPAAPA APAPAEKTPV KKKARKSAGA AKRKASGPPV SELITKAVAA
- Sequence homology:
- Cow: 93%
- Dog: 100%
- Guinea Pig: 93%
- Human: 100%
- Mouse: 86%
- Rabbit: 100%
- Rat: 93%
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction into higher-order structures.
The HIST1H1E gene encodes a member of the histone H1 family, is intronless, and lacks a polyA tail, instead containing a palindromic termination element. It is located in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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