Thermo Fisher Scientific SPA17 Polyclonal Antibody
Thermo Fisher Scientific의 SPA17 Polyclonal Antibody는 인간 SPA17 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot에 적합합니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 액상 형태로 제공되고 -20°C에서 보관 가능합니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human SPA17 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607754 |
Product Specific Information
Peptide sequence:
MSIPFSNTHY RIPQGFGNLL EGLTREILRE QPDNIPAFAA AYFESLLEKR
Sequence homology:
Cow: 100%
Dog: 93%
Guinea Pig: 93%
Horse: 93%
Human: 100%
Mouse: 100%
Pig: 100%
Rabbit: 100%
Rat: 100%
Sheep: 100%
Zebrafish: 79%
Target Information
This gene encodes a protein present at the cell surface.
The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa), while the C-terminus has an IQ calmodulin-binding motif.
The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion.
Initially characterized by its role in sperm binding to the zona pellucida of the oocyte, SPA17 is also implicated in immune cell migration and metastasis.
A retrotransposed pseudogene is present on chromosome 10q22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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