Thermo Fisher Scientific FCN3 Monoclonal Antibody (4B4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1:500-1:1,000

-

Immunoprecipitation (IP)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgM, kappa

Class

Monoclonal

Type

Antibody

Clone

4B4

Immunogen

FCN3 (AAH20731, 1 a.a. approximately 288 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Ficolin 3,uniProtId:O75636-1,ncbiNodeId:9606,antigenRange:1-299,antigenLength:299,antigenImageFileName:H00008547-M01A_Ficolin_3_O75636-1_House_mouse.svg,antigenImageFileNamePDP:H00008547-M01A_Ficolin_3_O75636-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MDLLWILPSL WLLLLGGPAC LKTQEHPSCP GPRELEASKV VLLPSCPGAP GSPGEKGAPG PQGPPGPPGK MGPKGEPGPR NCRELLSQGA TLSGWYHLCL PEGRALPVFC DMDTEGGGWL VFQRRQDGSV DFFRSWSSYR AGFGNQESEF WLGNENLHQL TLQGNWELRV ELEDFNGNRT FAHYATFRLL GEVDHYQLAL GKFSEGTAGD SLSLHSGRPL TTYDADHDSS NSNCAVIVHG AWWYASCYRS NLNGRYAVSE AAAHKYGIDW ASGRGVGHPY RRVRMMLR

Target Information

H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.