Thermo Fisher Scientific Slco1a1 Polyclonal Antibody
Slco1a1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 마우스 및 랫트 반응성, Western blot, IHC, ICC/IF 등 다양한 응용 가능. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from rat Slco1a1 (amino acids 2–90) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA and 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The organic anion transporting polypeptides (OATPs), including OATP-A (also known as OATP1, OATP1A2, and SLC21A3) and OATP-C (also known as OATP2, SLC21A6, and LST1), mediate hepatic uptake of cardiac glycosides.
OATP-C expression is inducible by phenobarbital and pregnenolone-16α-carbonitrile, enhancing liver capacity to extract cardiac glycosides from plasma.
OATP-A is expressed in liver and kidney, mediating sodium-independent uptake of anionic steroid conjugates such as dehydroepiandrosterone sulfate, estradiol-17-glucuronide, and prostaglandin.
OATP-C is exclusively expressed in the liver and localized to the basolateral hepatocyte membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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