Thermo Fisher Scientific PTK7 Monoclonal Antibody (4C6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

ELISA (ELISA)

1 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

4C6

Immunogen

PTK7 (NP_002812, 36 a.a. approximately 145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PTK7,uniProtId:Q13308-1,ncbiNodeId:9606,antigenRange:36-145,antigenLength:1070,antigenImageFileName:H00005754-M02_PTK7_Q13308-1_House_mouse.svg,antigenImageFileNamePDP:H00005754-M02_PTK7_Q13308-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: KQPSSQDALQ GRRALLRCEV EAPGPVHVYW LLDGAPVQDT ERRFAQGSSL SFAAVDRLQD SGTFQCVARD DVTGEEARSA NASFNIKWIE AGPVVLKHPA SEAEIQPQTQ

Target Information

CCK4 may function as a cell adhesion molecule. Although it belongs to the insulin receptor subfamily of the Tyr protein kinases, it likely lacks the catalytic activity of a tyrosine kinase. It may be connected to the pathophysiology of colon carcinomas and/or may represent a tumor progression marker. This Type I membrane protein is highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes, but weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle, and not in colon. It is also expressed in erythroleukemia cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.