Thermo Fisher Scientific Carbonic Anhydrase VB Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Carbonic Anhydrase VB. Recombinant protein control fragment (Product #RP-92233). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Carbonic Anhydrase VB,uniProtId:Q9Y2D0-1,ncbiNodeId:9606,antigenRange:176-279,antigenLength:317,antigenImageFileName:PA5-52959_Carbonic_Anhydrase_VB_Q9Y2D0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52959_Carbonic_Anhydrase_VB_Q9Y2D0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639280

Product Specific Information

Immunogen sequence: GLAVIGVFLK LGKHHKELQK LVDTLPSIKH KDALVEFGSF DPSCLMPTCP DYWTYSGSLT TPPLSESVTW IIKKQPVEVD HDQLEQFRTL LFTSEGEKEK RMVD

Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Target Information

Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide.CAs show extensive diversity in their distribution and subcellular localization.They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA VB, also known as carbonate dehydratase VB, is one of two isoforms of CA V. It localizes to the mitochondria and is involved in metabolic processes. CA VB is predominantly expressed in heart, pancreas, lung, placenta, kidney and skeletal muscle. It exhibits highest homology with family member CA VA (the second isoform of CA V); however, unlike CA VA, it is not expressed in the liver, suggesting that it plays a significantly different physiological role.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.