Thermo Fisher Scientific NFX1 Polyclonal Antibody
Rabbit에서 생산된 NFX1 단백질에 대한 다클론 항체로, 인간 NFX1을 표적으로 함. 비결합형 액상 형태이며 로트별 농도 지정. MHC class II 유전자 발현 조절 연구에 적합. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific NFX1 Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NFX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Lot-Specific |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663212 |
Product Specific Information
Immunogen sequence:
KELPCTSLKSE DATFMCDKRC NKKRLCGRHK CNEICCVDKE HKCPLICGRK LRCGLHRCEE PCHRGNCQTC WQASFDELTC HCGASVIYPP VPCGTRPPEC TQTCARVHEC DHPVYHSCHS EEKCPPCTFL TQKWC
- Highest antigen sequence identity to the following orthologs: mouse 99%, rat 99%.
Target Information
MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes.
NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro.
The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.
Three alternative splice variants, each of which encodes a different isoform, have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-66008_NFX1_Q12986-1_Rabbit_PDP.jpeg, PA5-66008_NFX1_Q12986-1_Rabbit.svg)
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