Thermo Fisher Scientific Fetal Hemoglobin Test Kit, FITC
태아 헤모글로빈(HbF)을 인식하는 FITC 표지 단클론 항체 기반 검사 키트. 유세포분석법으로 태아 적혈구를 식별 및 정량화. 태아-모체 출혈 확인과 면역글로불린 투여 판단에 활용. 인체 시료용 체외진단(IVD) 제품.
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Invitrogen™ Fetal Hemoglobin Test Kit, FITC
The Fetal Hemoglobin (HbF) Test is based on a monoclonal antibody directed to fetal hemoglobin (hemoglobin F). This antibody is conjugated with fluorescein (FITC), providing high absorptivity, excellent fluorescence quantum yield, and good water solubility.
This reagent is intended for identification and enumeration of fetal red blood cells. Fetal cells are identified by the presence of fetal hemoglobin using a flow cytometric method. The Fetal Hemoglobin Test may be used as an aid in identifying fetal-maternal hemorrhage and determining the need for immunoprophylaxis with immune globulin.
Antibody Specifications
| 항목 | 내용 |
|---|---|
| Description | Fetal Hemoglobin F (HbF), mouse IgG1 monoclonal |
| Label | Fluorescein (FITC) |
| Validated Application | Flow Cytometry |
| Species Reactivity | Human |
| Ex/Em and Laser Configuration | 488/519 nm, blue laser |
| Clone ID | HbF-1 |
| Regulatory Status | IVD |
Antibody Characteristics
- Clinical relevance
- In vitro diagnostic
Clinical Relevance
The Fetal Hemoglobin Test contains a monoclonal antibody directed to HbF that specifically recognizes fetal hemoglobin in fetal erythrocytes. It allows enumeration of fetal erythrocytes in maternal circulation resulting from fetal-maternal hemorrhage.
Hemorrhage from an Rh⁺ fetus into the circulation of an Rh⁻ mother may lead to Rh-reactive antibody formation, potentially causing Rh hemolytic anemia in subsequent Rh⁺ fetuses.
Although fetal erythrocytes in maternal circulation are usually minimal, substantial hemorrhage may occur due to trauma or placental defects.
Erythrocytes containing fetal hemoglobin (F cells) may also be found in adults at lower levels. Elevated F cells can occur in hereditary persistence of fetal hemoglobin or certain anemic disorders such as sickle cell anemia and thalassemia major.
In Vitro Diagnostic
For In Vitro Diagnostic Use.
Related Links
제품 사양
| 항목 | 내용 |
|---|---|
| 항체 콘주게이트 | Classic Dyes (e.g. FITC, TRITC), FITC (Fluorescein) |
| CE 마커 | Yes |
| 검출 방법 | Fluorescence |
| 형식 | Kit |
| 유형 | Hemoglobin Test Kit |
| 용도(애플리케이션) | Flow Cytometry Antibodies and Secondary Detection |
| 라벨 또는 염료 | FITC (Fluorescein) |
| 수량 | 100 Tests |
| 배송 조건 | Wet Ice |
| 종 | Mouse |
| Unit Size | Each |
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