Thermo Fisher Scientific GBP5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:5,000-1:10,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GBP5. Recombinant protein control fragment (Product #RP-94338). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GBP5,uniProtId:Q96PP8-1,ncbiNodeId:9606,antigenRange:476-586,antigenLength:586,antigenImageFileName:PA5-83024_GBP5_Q96PP8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-83024_GBP5_Q96PP8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2790180

Product Specific Information

Immunogen sequence: TDQALTETEK KKKEAQVKAE AEKAEAQRLA AIQRQNEQMM QERERLHQEQ VRQMEIAKQN WLAEQQKMQE QQMQEQAAQL STTFQAQNRS LLSELQHAQR TVNNDDPCVL L

Target Information

The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.