Thermo Fisher Scientific PDE10A Recombinant Rabbit Monoclonal Antibody (8J7E5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

8J7E5

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 439-779 of human PDE10A. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PDE10A,uniProtId:Q9Y233-1,ncbiNodeId:9606,antigenRange:439-779,antigenLength:779,antigenImageFileName:MA5-55515_PDE10A_Q9Y233-1_Rabbit.svg,antigenImageFileNamePDP:MA5-55515_PDE10A_Q9Y233-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.49 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen Sequence: SICTSEEWQG LMQFTLPVRL CKEIELFHFD IGPFENMWPG IFVYMVHRSC GTSCFELEKL CRFIMSVKKN YRRVPYHNWK HAVTVAHCMY AILQNNHTLF TDLERKGLLI ACLCHDLDHR GFSNSYLQKF DHPLAALYST STMEQHHFSQ TVSILQLEGH NIFSTLSSSE YEQVLEIIRK AIIATDLALY FGNRKQLEEM YQTGSLNLNN QSHRDRVIGL MMTACDLCSV TKLWPVTKLT ANDIYAEFWA EGDEMKKLGI QPIPMMDRDK KDEVPQGQLG FYNAVAIPCY TTLTQILPPT EPLLKACRDN LSQWEKVIRG EETATWISSP SVAQKAAASE D

Target Information

Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.