Thermo Fisher Scientific Cystatin 8 Polyclonal Antibody
Thermo Fisher Scientific의 Cystatin 8 Polyclonal Antibody는 Mouse 시료에 반응하는 Rabbit IgG 기반 항체입니다. Western blot 및 ELISA에 적합하며, 고순도 Affinity Chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 -20°C에서 안정적으로 유지됩니다.
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- PA588438
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 53–142 of human CST8 (NP_005483.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.36 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804913 |
Product Specific Information
- Immunogen sequence: MQEYNKESED KYVFLVVKTL QAQLQVTNLL EYLIDVEIAR SDCRKPLSTN EICAIQENSK LKRKLSCSFL VGALPWNGEF TVMEKKCEDA
- Positive Samples: Mouse testis, Mouse liver
Target Information
The cystatin superfamily is a well-established family of cysteine protease inhibitors. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, while some also inhibit legumain family enzymes.
The CRES (cystatin-related epididymal spermatogenic) protein defines a new subgroup in the family 2 cystatins of the cystatin superfamily.
CRES proteins lack two of the three consensus sites necessary for the cystatin inhibition of C1 cysteine proteases. They are preferentially expressed in postmeiotic germ cells, the proximal caput epididymidis, and anterior pituitary gonadotrophs.
As a member of the CRES subfamily, Cystatin 8 is a 142 amino acid protein expressed in the proximal caput region of the epididymis, where it performs a specialized role during sperm development and maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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