Thermo Fisher Scientific GTPBP2 Polyclonal Antibody
Rabbit polyclonal antibody against human GTPBP2 단백질로, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 0.3 mg/mL 농도의 액상 형태. PBS(glycerol 포함) 용액에 보관하며, 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human GTPBP2. Recombinant protein control fragment (Product # RP-105855) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664650 |
Product Specific Information
Immunogen sequence:
EFQVDEIYTVP EVGTVVGGTL SSGICREGDQ LVVGPTDDGC FLELRVCSIQ RNRSACRVLR AGQAATLALG DFDRALLRKG MVMVSPEM
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
Small G proteins act as molecular switches regulating various cellular processes such as nuclear transport, signal transduction, membrane trafficking, and protein synthesis.
GTPBP2 (GTP-binding protein 2) is a 602 amino acid G protein expressed in kidney, skeletal muscle, testis, brain, and thymus, but not in liver. Its expression is enhanced by γ-interferon stimulation in HeLa cells, THP-1 cells, and thioglycollate-elicited mouse peritoneal macrophages.
There are four isoforms of GTPBP2 resulting from alternative splicing. Mutation in the gene encoding GTPBP1 does not lead to phenotypic abnormalities, suggesting possible genetic redundancy. GTPBP2 shares 44% sequence similarity with GTPBP1 and overlaps in expression pattern, implying potential compensatory functions.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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