Thermo Fisher Scientific XPC Polyclonal Antibody
Thermo Fisher Scientific의 XPC Polyclonal Antibody는 인간 XPC 단백질(잔기 890–940)에 대한 토끼 IgG 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 액상 형태로 제공됩니다. 4°C에서 보관하며, 다양한 포유류 종과 교차 반응이 예측됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 890 and 940 of Human xeroderma pigmentosum, complementation group C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Dog, Orangutan, Monkey, Gorilla, and Chimpanzee
Target Information
This gene encodes a component of the nucleotide excision repair (NER) pathway. The NER pathway includes multiple components such as Xeroderma pigmentosum (XP) A–G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A.
XPC plays an important role in the early steps of global genome NER, particularly in damage recognition, open complex formation, and repair protein complex formation.
Mutations in this gene or other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight and early development of carcinomas.
Alternatively spliced transcript variants have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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