Thermo Fisher Scientific Desmoglein 2 Polyclonal Antibody
Rabbit polyclonal antibody against human Desmoglein 2 (DSG2). Suitable for Western blot in human, mouse, and rat samples. High purity (>95%) and antigen affinity purified. Supplied in PBS with 50% glycerol for stable storage.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human DSG2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803866 |
Product Specific Information
Purity is greater than 95% as determined by SDS-PAGE.
Target Information
Desmosomes are cell-cell junctions found in epithelial, myocardial, and certain other cell types. Three desmoglein subfamily members have been identified, all belonging to the cadherin cell adhesion molecule superfamily. These genes are clustered on chromosome 18. Desmoglein 2 has been identified as the autoantigen in the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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