Thermo Fisher Scientific DNASE2B Polyclonal Antibody
DNASE2B 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화됨. 인간 단백질에 반응하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 4°C 단기, -20°C 장기 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 84–309 of Human DNASE2B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.96 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548865 |
Product Specific Information
- Recommended positive controls: A549, HeLa, HepG2, HCT116
- Predicted reactivity: Bovine (88%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. DNase II is a well-characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH.
Unlike DNase II, which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs.
The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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