Thermo Fisher Scientific FBLIM1 Polyclonal Antibody
Human FBLIM1 단백질을 인식하는 Rabbit Polyclonal 항체로, 면역세포화학(ICC/IF)에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼(40% 글리세롤) 내 액상 형태로 제공됩니다. 세포 접착 및 세포골격 연구에 활용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human FBLIM1. Recombinant protein control fragment (Product #RP-107897) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664218 |
Product Specific Information
Immunogen sequence:
SKPEKRVASSV FITLAPPRRD VAVAEEVRQA VCEARRGRPW EAPAPMKTPE
AGLAGRPSPW TTPGRAAATV PAAPMQLFNG GCPPPPPVLD GE- Highest antigen sequence identity to the following orthologs:
- Mouse: 63%
- Rat: 67%
Target Information
This gene encodes a protein with:
- An N-terminal filamin-binding domain
- A central proline-rich domain
- Multiple C-terminal LIM domains
This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. It is involved in the assembly and stabilization of actin filaments and likely plays a role in modulating cell adhesion, morphology, and motility. Additionally, it localizes to the nucleus and may influence cardiomyocyte differentiation through interaction with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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