Thermo Fisher Scientific SLC16A2 Polyclonal Antibody
Rabbit polyclonal antibody against human SLC16A2 for Western blot applications. Recognizes internal region peptide of SLC16A2. Supplied as liquid, 1 mg/mL concentration, stored at -20°C. For research use only.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SLC16A2 Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human SLC16A2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555844 |
Target Information
Monocarboxylates such as lactate and pyruvate play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and cessation of glycolysis. To maintain glycolysis at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), functioning as proton symports and stereoselective for L-lactate. The MCT family consists of at least eight members (MCT1–8) containing 10–12 transmembrane-helical domains, with both termini located in the cytoplasm. Defects in the gene encoding MCT8 (SLC16A2) can cause monocarboxylate transporter 8 deficiency, leading to X-linked psychomotor retardation and abnormal thyroid levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.