Thermo Fisher Scientific Lamin B Receptor Polyclonal Antibody
Thermo Fisher Scientific의 Lamin B Receptor Polyclonal Antibody는 인간 LBR 단백질을 인식하는 토끼 유래 폴리클로날 항체입니다. Western blot 및 ICC/IF에 사용 가능하며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.2–1 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human LBR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607827 |
Product Specific Information
Peptide sequence:
GANSQKNAFR KNPSDPKLAH LKTIHTSTGK NLLVSGWWGF VRHPNYLGDL
Sequence homology:
Cow: 86%
Dog: 93%
Guinea Pig: 86%
Horse: 93%
Human: 100%
Mouse: 93%
Pig: 93%
Rabbit: 93%
Rat: 100%
Yeast: 77%
Zebrafish: 79%
Target Information
The protein encoded by this gene belongs to the ERG4/ERG24 family. It is localized in the nuclear envelope inner membrane and anchors the lamina and heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene have been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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