Thermo Fisher Scientific Phospho-Ask1 (Ser83) Recombinant Rabbit Monoclonal Antibody (Ask1S83-G4), FITC
FITC 형광 표지된 recombinant rabbit monoclonal antibody로, 인간, 마우스, 랫트의 phospho-Ask1 (Ser83)을 검출 가능. Flow cytometry에 최적화된 사용 조건 제공. Protein A/G 정제, PBS+BSA buffer, 4°C 암소 보관.
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Thermo Fisher Scientific Phospho-Ask1 (Ser83) Recombinant Rabbit Monoclonal Antibody (Ask1S83-G4), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Ask1S83-G4 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser83 of human phospho Ask1 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897196 |
Additional Formats
- Unconjugated: MA5-36973
- APC: MA5-36976
- PE: MA5-36974
- Request custom conjugation available
Target Information
MAP3K5 (ASK1) is a serine/threonine kinase abundantly expressed in human heart and pancreas. It is activated by various stimuli including cytokines, growth factors, and environmental stresses. ASK1 activates MAPKKs (MKK4 and MKK6), which in turn activate JNK and p38 MAP kinases. ASK1/MAPKKK5 is activated by TNFR and Fas through interaction with TRAF family members and Daxx. Overexpression of ASK1 induces apoptosis, while inactive ASK1 inhibits TNF-α-induced apoptosis. ASK1 is expressed in various human and mouse tissues.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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