Thermo Fisher Scientific HPD Polyclonal Antibody
Thermo Fisher Scientific의 HPD Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가지며, Western blot 및 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 항체로, 연구용으로 안정적인 신호 검출을 제공합니다.
- 카탈로그번호
- PA558343
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HPD. Recombinant protein control fragment (Product #RP-97847) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642533 |
Product Specific Information
- Immunogen sequence:
REPWVEQDKF GKVKFAVLQT YGDTTHTLVE KMNYIGQFLP GYEAPAFMDP LLPKLPKCSL EMIDHIVGNQ P - Highest antigen sequence identity to orthologs:
- Mouse: 85%
- Rat: 83%
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity. Recently, a serine protease called Omi/HtrA2 was found to be released from mitochondria upon induction of apoptosis. Omi binds to IAP and contains a conserved IAP-binding motif (AVPS) at its N terminus. Deregulated expression of Omi in the cytoplasm induces apoptosis, suggesting its role in the mitochondrial apoptotic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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