Thermo Fisher Scientific PFKFB2 Polyclonal Antibody
Thermo Fisher Scientific의 PFKFB2 Polyclonal Antibody는 마우스 PFKFB2 단백질을 인식하는 토끼 유래 다클론 항체입니다. Western blot에 적합하며, 고순도의 Affinity chromatography 정제 방식으로 제조되었습니다. PBS 기반 저장 용액에 2% sucrose와 0.09% sodium azide를 포함합니다.
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Applications
- Western Blot (WB): Tested at 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of mouse PFKFB2 (UniProt ID: P70265-1, amino acids 337–386) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689838 |
Product Specific Information
This target displays homology in the following species:
- Cow: 93%
- Dog: 100%
- Guinea Pig: 93%
- Horse: 100%
- Human: 100%
- Mouse: 100%
- Rabbit: 93%
- Rat: 100%
- Yeast: 79%
- Zebrafish: 86%
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. Through this mechanism, protein kinases mediate most signal transduction in eukaryotic cells, regulating metabolism, transcription, cell cycle progression, cytoskeletal rearrangement, cell movement, apoptosis, and differentiation.
With over 500 gene products, the protein kinase family is one of the largest in eukaryotes. It is classified into eight major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group includes:
- PKA & PKG (cyclic nucleotide-regulated)
- PKC (diacylglycerol-activated/phospholipid-dependent)
- RAC/Akt (related to PKA and PKC)
- ARK (G protein-coupled receptor kinases)
- RSK (ribosomal protein S6 kinases)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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