Thermo Fisher Scientific GHSR Polyclonal Antibody
인간 GHSR 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 5–7.5 µg/mL 농도로 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 에너지 항상성과 성장호르몬 분비 연구에 적합합니다.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 5–7.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 13 amino acid peptide from N-terminal extracellular domain of human GHS-R1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2111727 |
Product Specific Information
PA1-32875 detects GHSR from human samples.
Target Information
Growth hormone secretagogue receptor 1a (GHSR) is a member of the G-protein coupled receptor family. GHSR may play a role in energy homeostasis and the regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionarily conserved in fish and swine.
Transcript 1a encodes the functional receptor for the Ghrelin ligand, defining a neuroendocrine pathway for growth hormone release.
Transcript 1b retains the intron and does not function as a receptor for Ghrelin but may attenuate the activity of isoform 1a.
Mutations in this gene can cause isolated partial growth hormone deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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