Thermo Fisher Scientific GABA(A) R gamma-1 Polyclonal Antibody
Rabbit polyclonal antibody targeting GABA(A) receptor gamma-1 subunit. Validated for WB and IHC in mouse and rat samples. Lyophilized, unconjugated form for research use only. Specific to GABRG1, ideal for neuroscience and receptor studies.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from amino acid region 350–450 of rat GABA(A) R gamma-1 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: GABRG1.
Target Information
Gabrg1 encodes a protein belonging to the ligand-gated ionic channel family. It is an integral membrane protein that inhibits neurotransmission by binding to the benzodiazepine receptor and opening a chloride channel.
The Gabrg1 gene is clustered with three other family members on chromosome 4.
GABAA receptors are members of the Cys-loop family of ligand-gated ion channels and, along with GABAB receptors, mediate the inhibitory effects of GABA.
Structurally, Gabrg1 proteins are pentameric, consisting of five subunits from different families.
Diseases associated with GABRG1 include Alcohol Dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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