Thermo Fisher Scientific DSPP (Disuccinimidyl Phenyl Phosphonic Acid, PhoX), 50 mg

Thermo Scientific™ DSPP (Disuccinimidyl Phenyl Phosphonic Acid, PhoX)

Mass Spectrometry Compatible Crosslinkers

Improve mass spectrometry detection of crosslinked proteins and interactions with DSPP and TBDSPP heterotrifunctional crosslinkers.

Chemical crosslinking in combination with mass spectrometry is a powerful method to improve protein characterization, and to identify protein-protein interactions. This method has been applied to recombinant and native protein complexes, and more recently, to whole cell lysates or intact unicellular organisms in efforts to identify protein-protein interactions on a global scale. The enrichment feature of DSPP and TBDSPP improves detection of crosslinked proteins by reducing sample complexity through separation of crosslinked from non-crosslinked peptides.

제품 사양

주요 특징

• 질량분석 기반 단백질-단백질 상호작용 연구에 적합
• 교차결합 단백질 검출 향상 및 샘플 복잡도 감소
• 수용성, 비세포투과성, 고체 형태의 화학적 라벨링 시약
• 50 mg 단위로 제공