Thermo Fisher Scientific Bcl-6 (Follicular Lymphoma Marker) Monoclonal Antibody (BCL6/1475)
Bcl-6 단백질을 인식하는 단클론 항체로, 여포성 림프종 및 기타 B세포 림프종 연구에 적합. Western blot과 peptide array에 사용 가능. 인간 시료 반응성, 마우스 IgG1 아이소타입. 단백질 A/G로 정제된 액상 항체.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BCL6/1475 |
| Immunogen | Recombinant human Bcl-6 protein fragment (around aa256–389) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas.
Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas, and rearrangements have been detected in 33%–45% of diffuse large B-cell lymphomas.
It has been detected immunohistochemically in follicular lymphomas, diffuse large B-cell lymphomas, Burkitt’s lymphomas, and nodular lymphocyte predominant Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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