Thermo Fisher Scientific Phospho-Cdk2 (Tyr15) Monoclonal Antibody (2A1)
Rabbit monoclonal antibody recognizing phosphorylated Cdk2 (Tyr15). Validated for Western blot at 1:1,000 dilution. Supplied as liquid, 1 mg/mL concentration, stored at -20°C. For research use only.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A1 |
| Immunogen | Synthetic peptide derived from human Cdk2 (Y15), around 1–50aa (phospho Y15) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
CDK2/cyclinO is a member of the cyclin-dependent protein kinase family complexed to CyclinO. CyclinO was used as a specific protein isoform name for the UNG gene, which is localized exclusively in the nucleus. In addition, CyclinO shows significant uracil-DNA glycosylase activity. CDK2/cyclinO protein levels increase during G1 phase and are turned over during the cell cycle. Cyclin A–cdk2 levels peak at the G1/S transition, and both cdk2 and cyclin A are associated with DNA in the initiation complex during replication. Rb protein acts as a substrate for cdk2–cyclin E and/or cdk2–cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1, S, and G2 phases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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