Thermo Fisher Scientific Human IL-16 Synthetic Peptide

Thermo Fisher Scientific Human IL-16 Synthetic Peptide

Applications

• Control (Ctrl): Assay-dependent
• Blocking Assay (BLOCK): Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 14 amino acids near the amino terminus of human IL-16.
PEP-0789 can be used as a blocking peptide with polyclonal antibody PA5-20671.

Target Information

The protein encoded by IL-16 is a pleiotropic cytokine that functions as:

• A chemoattractant
• A modulator of T cell activation
• An inhibitor of HIV replication

The signaling process of IL-16 is mediated by CD4.
Proteolytic processing of IL-16 yields two functional proteins:

• The secreted C-terminal peptide (cytokine function)
• The N-terminal product (possible role in cell cycle control)

Caspase 3 is involved in the proteolytic processing of this protein.
Alternate splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.