Thermo Fisher Scientific CLDN6 Monoclonal Antibody (OTI2H1), TrueMAB
인간 CLDN6 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot 및 Immunocytochemistry에 적합. TrueMAB 형식의 고순도 항체이며, 1 mg/mL 농도로 PBS/BSA/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CLDN6 Monoclonal Antibody (OTI2H1), TrueMAB
Applications and Tested Dilution
- Western Blot (WB): 1:500
- Immunocytochemistry (ICC/IF): 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H1 |
| Immunogen | Full length human recombinant protein of human CLDN6 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet.
This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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