
Thermo Fisher Scientific Myeloperoxidase/MPO Recombinant Rabbit Monoclonal Antibody (MPO/33R)
Recombinant rabbit monoclonal antibody against human Myeloperoxidase (MPO). Validated for WB and IHC applications. High purity, unconjugated form, suitable for research use only. Stable at -20°C with no preservative for consistent performance.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MPO/33R |
| Immunogen | Recombinant fragment (around aa150–250) of human MPO protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into light and heavy chains. The mature MPO forms a tetramer composed of 2 light chains and 2 heavy chains. This enzyme generates hypohalous acids essential for the microbicidal activity of neutrophils. Diseases associated with MPO include Myeloperoxidase Deficiency and Familial Alzheimer’s Disease type 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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