Thermo Fisher Scientific GRIK5/KA2 Polyclonal Antibody
GRIK5/KA2 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간, 생쥐, 랫트에 반응합니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능하며 Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- BS-12033R
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human GRIK5/KA2 (amino acids 201–300) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes.
Grik5, also known as kainate-preferring glutamate receptor subunit KA2, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels.
Grik5 is highly homologous to the related ionotropic glutamate receptor Grik4 (KA1). Like Grik4, Grik5 does not form homomeric channels but instead forms heteromers with Grik2.
In Grik2- but not Grik1- mice, Grik5 surface expression is greatly reduced in neurons, indicating that Grik2/Grik5 heteromers are required for exit from the endoplasmic reticulum to the cell surface.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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