Thermo Fisher Scientific ZBTB6 Polyclonal Antibody
인간 ZBTB6 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:200–1:500 희석 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 뇌에서 높은 발현을 보이는 ZBTB6 연구용에 적합.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZBTB6. Recombinant protein control fragment (Product #RP-101569) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2649782 |
Product Specific Information
Immunogen sequence:
CTEPLSKYLE IDLSMKNNNQ HTDLCQSSDP DVKNEDENSD KDCEIIEISE DSPVNIDFHV K
Antigen sequence identity:
- Mouse: 92%
- Rat: 89%
Target Information
The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk, and bab) domain.
ZBTB6 (also known as ZNF482) is highly expressed in the brain. While little is known about ZBTB6, other ZBTB proteins such as ZBTB4 bind methylated DNA and repress transcription.
Another ZBTB family member, ZBTB5, also acts as a transcriptional repressor and can interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain.
This suggests that ZBTB6 may also function as a transcriptional repressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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