Thermo Fisher Scientific PG-C/Pepsinogen 2 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal Antibody로 다양한 응용(WB, IHC, ICC, ELISA)에 사용 가능. KLH 결합 합성 펩타이드(aa 21–120)로 면역화. 고순도 Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human PG-C, amino acids 21–120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. It consists of a single polypeptide chain and is derived from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid is necessary to convert the inactive enzyme and maintain the optimal acidity (pH 1–3) for pepsin function.
Pepsin effectively cleaves peptide bonds involving aromatic amino acids and exhibits broad specificity, preferring bonds involving phenylalanine and leucine. The amino acid composition of Pepsin C differs from that of pepsinogen and pepsin, particularly in the content of basic amino acids, glutamic acid, aspartic acid, leucine, and isoleucine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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