Thermo Fisher Scientific Phospho-VASP (Ser157) Polyclonal Antibody
Phospho-VASP (Ser157) 폴리클로날 항체로 인간, 마우스, 랫트 시료에 반응. WB, IHC, ICC/IF, ELISA 등 다양한 응용 가능. Protein A로 정제된 고순도 항체로 세포 부착 및 이동 관련 연구에 적합. 연구용으로만 사용.
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Thermo Fisher Scientific Phospho-VASP (Ser157) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human VASP around the phosphorylation site of Ser157 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. These proteins contain an EHV1 N-terminal domain that binds proteins with E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. The mid-region has a proline-rich domain that interacts with SH3 and WW domain-containing proteins, while the C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is linked to filamentous actin formation and plays a role in cell adhesion and motility. It may also participate in intracellular signaling that regulates integrin–extracellular matrix interactions. VASP is regulated by cyclic nucleotide-dependent kinases PKA and PKG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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