
Thermo Fisher Scientific Human Transthyretin Recombinant Protein
Recombinant human transthyretin protein expressed in E. coli. Lyophilized form with 1 mg/mL concentration. Functions as thyroxine and retinol-binding protein transporter. For research use only; not for diagnostic or resale purposes.
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Thermo Fisher Scientific Human Transthyretin Recombinant Protein
Applications
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Expression System | E. coli |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Product Specific Information
After reconstitution, store at -80ºC and avoid freeze and thaw cycles.
Target Information
Transthyretin (TTR), also known as prealbumin, is a plasma protein that acts as a transporter for thyroxine and retinal-binding protein. It is primarily produced in the liver and secreted into plasma. TTR constitutes about 25% of cerebrospinal fluid (CSF) protein, suggesting selective transport across the blood-CSF barrier or synthesis within the central nervous system. It is found in neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. Over 40 mutations in the TTR gene have been reported to be associated with amyloid deposition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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