Thermo Fisher Scientific BTBD7 Polyclonal Antibody
BTBD7 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human 및 Mouse 반응성. Rabbit IgG 기반, 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용.
- 카탈로그번호
- BTBD-701AP
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within amino acid region 1050–1150 on human BTBD7 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
BTBD7 acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. It is induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering factor SNAIL2 and suppression of E-cadherin levels. This process alters cell morphology and reduces cell-cell adhesion, stimulating cell separation at the base of forming clefts through local, dynamic intercellular gap formation and promoting cleft progression.
[Source: UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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