Thermo Fisher Scientific COMP Polyclonal Antibody
COMP 단백질을 표적으로 하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합함. Rabbit IgG 기반, Protein A로 정제된 액상 형태이며, -20°C에서 보관. 연구용으로만 사용 가능.
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카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human COMP, amino acids 221–320 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
COMP (Cartilage Oligomeric Matrix Protein) is a noncollagenous extracellular matrix protein composed of five identical glycoprotein subunits, each containing EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization occurs through a five-stranded coiled coil and disulfide bonds. COMP interacts with other ECM proteins such as collagen in a divalent cation-dependent manner. Mutations in COMP can lead to osteochondrodysplasias including pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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