Thermo Fisher Scientific FGFR1OP Polyclonal Antibody
Rabbit polyclonal antibody recognizing human FGFR1OP protein. Validated for ICC/IF applications at 0.25–2 µg/mL. Purified by antigen affinity chromatography and supplied in PBS with 40% glycerol. Suitable for research use only.
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Applications
- Immunocytochemistry (ICC/IF)
Tested dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human FGFR1OP. Recombinant protein control fragment (Product #RP-107846) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2662306 |
Product Specific Information
Immunogen sequence:
GDSFFDDPIPK PEKTYGLRKE PRKQAGSLAS LSDAPPLKSG LSSLAGAPSL KDSESKRGNT VL
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 84%
Target Information
The FGFR1OP gene encodes a largely hydrophilic protein, postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation fusing FGFR1OP and FGFR1 has been identified in certain myeloproliferative disorders. The resulting chimeric protein contains the N-terminal leucine-rich region of FGFR1OP fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants encoding different proteins have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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