Thermo Fisher Scientific OSGEPL1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human OSGEPL1. Recombinant protein control fragment (Product #RP-89224). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OSGEPL1,uniProtId:Q9H4B0-1,ncbiNodeId:9606,antigenRange:55-185,antigenLength:414,antigenImageFileName:PA5-56541_OSGEPL1_Q9H4B0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56541_OSGEPL1_Q9H4B0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645095

Product Specific Information

Immunogen sequence: DETGNVLGEA IHSQTEVHLK TGGIVPPAAQ QLHRENIQRI VQEALSASGV SPSDLSAIAT TIKPGLALSL GVGLSFSLQL VGQLKKPFIP IHHMEAHALT IRLTNKVEFP FLVLLISGGH CLLALVQGVS D

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.

Target Information

OSGEPL1, also known as Qri7, is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as 3 alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine. The gene that encodes OSGEPL1 contains about 16,568 bases and maps to human chromosome 2q32.2. Consisting of 237 million bases, chromosome 2 encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstrom syndrome, is due to mutations in the ALMS1 gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.