
Thermo Fisher Scientific FAM83D Polyclonal Antibody
FAM83D 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot에 최적화됨. 인간 시료에 반응하며, 액상 형태로 제공됨. 고순도 친화성 크로마토그래피로 정제되어 연구용으로 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human FAM83D |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691288 |
Product Specific Information
This target displays homology in the following species:
- Horse: 79%
- Human: 100%
- Mouse: 86%
- Rabbit: 86%
- Rat: 79%
Target Information
Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition.
Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC (PubMed:24344117).
May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade (PubMed:25646692).
May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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