Thermo Fisher Scientific CAMKK1 Monoclonal Antibody (1F6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

1F6

Immunogen

CAMKK1 (AAH31647, 1 a.a. approximately 520 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CaMKK alpha,uniProtId:Q8N5S9-1,ncbiNodeId:9606,antigenRange:1-505,antigenLength:505,antigenImageFileName:H00084254-M01A_CaMKK_alpha_Q8N5S9-1_House_mouse.svg,antigenImageFileNamePDP:H00084254-M01A_CaMKK_alpha_Q8N5S9-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MEGGPAVCCQ DPRAELVERV AAIDVTHLEE ADGGPEPTRN GVDPPPRARA ASVIPGSTSR LLPARPSLSA RKLSLQERPA GSYLEAQAGP YATGPASHIS PRAWRRPTIE SHHVAISDAE DCVQLNQYKL QSEIGKGAYG VVRLAYNESE DRHYAMKVLS KKKLLKQYGF PRRPPPRGSQ AAQGGPAKQL LPLERVYQEI AILKKLDHVN VVKLIEVLDD PAEDNLYLAL QNQAQNIQLD STNIAKPHSL LPSEQQDSGS TWAARSVFDL LRKGPVMEVP CDKPFSEEQA RLYLRDVILG LEYLHCQKIV HRDIKPSNLL LGDDGHVKIA DFGVSNQFEG NDAQLSSTAG TPAFMAPEAI SDSGQSFSGK ALDVWATGVT LYCFVYGKCP FIDDFILALH RKIKNEPVVF PEGPEISEEL KDLILKMLDK NPETRIGVPD IKLHPWVTKN GEEPLPSEEE HCSVVEVTEE EVKNSVRLIP SWTTVILVKS MLRKRSFGNP FEPQARREER SMSAPGNLLV

Target Information

CAMKK1 (CAMKKA) is a serine/threonine protein kinase family member, and belongs to the Ca2+/calmodulin-dependent protein kinase subfamily. The product of CaMKK alpha is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. CAMKK1 functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for CaMKK alpha. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.