Thermo Fisher Scientific SUV420H1 Polyclonal Antibody
SUV420H1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC(P), SPR 등 다양한 응용에 적합. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제, 안정적 액상 형태로 연구용에 최적화.
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Thermo Fisher Scientific SUV420H1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.2–2 µg/mL | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4–8 µg/mL | - |
| Surface Plasmon Resonance (SPR) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human SUV420H1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607567 |
Product Specific Information
Peptide Sequence:
NNGFNSGSGS SSTKLKIQLK RDEENRGSYT EGLHENGVCC SDPLSLLESR
Sequence Homology:
Dog: 86%
Guinea Pig: 92%
Horse: 92%
Human: 100%
Mouse: 91%
Rat: 93%
Target Information
Histone methyltransferase that specifically trimethylates Lys-20 of histone H4.
H4 Lys-20 trimethylation represents a specific tag for epigenetic transcriptional repression.
Mainly functions in pericentric heterochromatin regions, playing a central role in the establishment of constitutive heterochromatin.
KMT5B is targeted to histone H3 via interaction with RB1 family proteins (RB1, RBL1, RBL2).
Plays a role in myogenesis by regulating expression of target genes such as EID3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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