Thermo Fisher Scientific HDAC3 Monoclonal Antibody (OTI4E10), TrueMAB
HDAC3 단백질을 인식하는 Mouse monoclonal antibody로, Western blot에 최적화되어 있습니다. Human 시료 반응성이 확인되었으며, 고순도의 Affinity chromatography로 정제되었습니다. PBS/BSA/glycerol 완충액에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HDAC3 Monoclonal Antibody (OTI4E10), TrueMAB
Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–235 of human HDAC3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
HDAC3 belongs to the histone deacetylase/acuc/apha family and has histone deacetylase activity. It represses transcription when tethered to a promoter and may regulate transcription through interaction with the zinc-finger transcription factor YY1.
HDAC3 can also down-regulate p53 function, thereby modulating cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.