
Thermo Fisher Scientific Urotensin II Receptor Polyclonal Antibody
Thermo Fisher Scientific의 Urotensin II Receptor Polyclonal Antibody는 Rat 시료에 반응하는 Rabbit IgG 항체입니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 동결건조 형태로 제공되며, -20°C에서 보관 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)RPLDTVQRSKGYRK, corresponding to amino acid residues 154–167 of rat URIIR, 2nd intracellular loop |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 50 µL or 0.2 mL double distilled water (DDW), depending on sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, aliquot and keep at -20°C.
Avoid multiple freezing and thawing.
Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
The Urotensin-II receptor is highly expressed in the heart and pancreas, and also found in artery and smooth muscle.
Low transcript levels are observed in the brain, particularly in the thalamus and superior occipital gyrus.
G-protein Coupled Receptors (GPCRs) represent one of the largest families of signaling molecules, characterized by seven membrane-spanning helices and existing in both active and inactive forms.
Activation and regulation of GPCRs are key mechanisms in cellular signaling and pharmacological research.
Notably, GPCR-targeted drugs such as Zyprexa (Eli Lilly) and Claritin (Schering-Plough) have achieved significant success in mental health and allergy treatment markets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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