Thermo Fisher Scientific HMGB2 Polyclonal Antibody
HMGB2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 ELISA에 적합합니다. 인간 및 생쥐 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:5,000
ELISA
- Tested Dilution: 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 166–180 of Human HMGB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2635173 |
Product Specific Information
This antibody detects endogenous levels of total HMGB2 protein.
Target Information
HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. These proteins are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have shown that HMGB2 efficiently bends DNA and forms DNA circles, suggesting a role in promoting DNA flexibility and facilitating cooperative interactions between cis-acting proteins. It is also implicated in the final ligation step of DNA end-joining processes during double-strand break repair and V(D)J recombination.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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