Thermo Fisher Scientific PTPN7 Monoclonal Antibody (OTI3G2)
PTPN7 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간 시료 반응성. 고순도 친화 크로마토그래피 정제. 안정적 액상 형태로 -20°C 보관.
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- pk
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Thermo Fisher Scientific PTPN7 Monoclonal Antibody (OTI3G2)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G2 |
| Immunogen | Full length human recombinant protein of PTPN7 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.02 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725152 |
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This gene is preferentially expressed in hematopoietic cells and acts as an early response gene in lymphokine-stimulated cells. The noncatalytic N-terminus of PTPN7 interacts with MAP kinases and suppresses their activity.
PTPN7 is involved in T cell antigen receptor signaling through dephosphorylation of molecules related to the MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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