Thermo Fisher Scientific MMRN1 Polyclonal Antibody
MMRN1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 검증 완료. Protein A로 정제된 액상 형태, 1 mg/mL 농도. Human, Mouse, Rat 반응성. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- 1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human MMRN1 (amino acids 895–930) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Multimerin-1 (MMRN1), also known as EMILIN-4 or ECM (endothelial cell multimerin), is a 1,228 amino acid secreted protein containing one C1q domain, one EMI domain, and one EGF-like domain. It is synthesized in megakaryocytes and endothelial cells and found in liver, lung, and placenta. Multimerin-1 forms multimeric structures via disulfide bonds and functions as a carrier protein for platelet factor V, aiding in its stabilization and storage in platelets. It also acts as a ligand for select integrins, contributing to extracellular matrix adhesion. Mutations causing Multimerin-1 deficiency are linked to autosomal dominant bleeding disorders due to platelet factor malfunction. Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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